The Cancer Research UK Convergence Science Centre has two research themes: Convergence Discovery Research and Interventional Science, where significant opportunity exists for multidisciplinary research to accelerate progress. These two research themes are supported by underpinning initiatives in Clinical Drug Development, focusing on iterative and reverse translation, and in Data Science and Digital Pathology. Spanning discovery research to further our fundamental understanding of cancer, through disease detection and diagnosis to new ways to treat and monitor therapeutic efficacy in patients, the Centre has a broad ranging focus, brought together through the opportunities for convergence science to accelerate progress.